Booting Earth Optimization System
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Melarsoprol
Treatment for African trypanosomiasis
Typical Dosage: 1.8-3.6 mg/kg IV daily for 3-4 days, repeated after 7-10 days, total 3 series
Effectiveness
85%
Safety Score
25%
Clinical Trials
1
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
25
DangerousModerateSafe
Treatment Details
Dosage Range
1.8-3.6 mg/kg IV daily for 3-4 days, repeated after 7-10 days, total 3 series
Time to Effect
Within days, full effect after treatment completion
Treatment Duration
3.5 weeks (3 series of 3-4 daily injections)
Evidence Quality
MODERATENumber Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
80%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$200
Monitoring:$7,000
Side Effect Mgmt:$2,000
Total Annual:$9,200
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
POORQALYs Gained
2
Outcome-Based Costs
Cost per Responder
$10,824
Cost per Remission
$11,500
Melarsoprol Outcomes
for African trypanosomiasis
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+85%
Remission Rate
+80%
Common Side Effects
Reactive encephalopathy
+7%
Peripheral neuropathy
+10%
Myocardial damage
+5%
Vomiting
+50%
Death from side effects
+5%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov