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Rezum Water Vapor Thermal Therapy
Treatment for Benign Prostatic Hyperplasia
Effectiveness
70%
Safety Score
52%
Clinical Trials
16
Participants
4K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
52
DangerousModerateSafe
Treatment Details
Time to Effect
2 weeks (initial) to 3 months (full effect)
Treatment Duration
Single procedure (effects >4 years)
Evidence Quality
HIGHNumber Needed to Treat (NNT)
3(Treat 3 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
4(Treat 4 patients to see 1 additional serious adverse event)
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$200
Side Effect Mgmt:$100
Total Annual:$2,050
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$35,000/QALY
QALYs Gained
0.09
Outcome-Based Costs
Cost per Responder
$2,733
Comparison vs TURP
Cost Difference
$-2,000/year
Less expensive
QALY Difference
+0.05 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
10 active trials recruiting for Rezum Water Vapor Thermal Therapy in Benign Prostatic Hyperplasia
Study on Water Vapor Thermal Therapy
NCT06656689RECRUITING
300 participants
OBSERVATIONAL
Suwon, South Korea
Started: Jul 31, 2023
Optimized Water Vapor Thermal Therapy for Benign Prostatic Hyperplasia
NCT06607094NOT YET RECRUITINGNA
58 participants
INTERVENTIONAL
Started: Sep 1, 2024
Modified Water Vapor Thermal Therapy in Management of Patients With Large-volume Benign Prostatic Hyperplasia
NCT06596590NOT YET RECRUITINGNA
76 participants
INTERVENTIONAL
Nanjing, China
Started: Sep 1, 2024
Comparison Between Water Vapor Thermal Therapy and Prostatic Artery Embolization in Treatment of Benign Prostatic Hyperplasia
NCT07416227RECRUITINGNA
30 participants
INTERVENTIONAL
Cairo, Egypt
Started: Oct 1, 2025
Trial to Assess the Efficacy and Safety During Convective Radiofrequency Water Vapor Thermal Therapy (REZUM) for Benign Prostate Hyperplasia
NCT07017452NOT YET RECRUITINGPHASE3
48 participants
INTERVENTIONAL
Winnipeg, Canada
Started: Aug 1, 2025
Evaluation of the Optilume BPH Catheter System and the Rezum Water Vapor Therapy in Treating Benign Prostatic Hyperplasia
NCT06769997RECRUITINGNA
100 participants
INTERVENTIONAL
Montreal, Canada
Started: May 9, 2025
Comparing UroLift Experience Against Rezūm
NCT04338776ACTIVE NOT RECRUITINGNA
120 participants
INTERVENTIONAL
Los Angeles, United States +9 more
Started: Jan 22, 2021
Comparing Rezum and Urolift
NCT06820606RECRUITINGNA
120 participants
INTERVENTIONAL
Hong Kong, Hong Kong
Started: Jan 1, 2025
Comparing Water Vapour Thermal Therapy (Rezūm) and TURP
NCT05762198RECRUITINGNA
108 participants
INTERVENTIONAL
Hong Kong, Hong Kong
Started: May 1, 2023
Registry of MIUS for Benign Prostatic Obstruction
NCT07159165ENROLLING BY INVITATION
10K participants
OBSERVATIONAL
Samsun, Turkey (Türkiye)
Started: Jul 1, 2025
Completed Clinical Trials
8 completed trials for Rezum Water Vapor Thermal Therapy in Benign Prostatic Hyperplasia
Safety, Efficacy, and Short-Term Outcomes of Rezūm Water Vapor Thermal Therapy for Benign Prostatic Hyperplasia Under Local Anesthesia With Intravenous Sedation: A Single-Center Retrospective Study of 129 Patients in the Kurdistan Region of Iraq
NCT07507591COMPLETED
129 participants
OBSERVATIONAL
Sulaymaniyah, Iraq
Started: Sep 3, 2025
One-year Results After Single-center Water Vapor Thermal Therapy for Symptomatic Benign Prostatic Hyperplasia.
NCT06257654COMPLETED
71 participants
OBSERVATIONAL
Istanbul, Turkey (Türkiye) +1 more
Started: Jan 1, 2021
Rezum I Pilot Study for Benign Prostatic Hyperplasia
NCT02943070COMPLETEDNA
50 participants
INTERVENTIONAL
Brno, Czechia +2 more
Started: Mar 1, 2012
Long Term Follow up of Water Vapor Thermal Therapy (Rezum) for Benign Prostatic Hyperplasia (BPH)
NCT05982444COMPLETEDNA
86 participants
INTERVENTIONAL
Helwan, Egypt
Started: Mar 1, 2021
Holmium Laser Enucleation Of the Prostate Versus Water Vapor Therapy Of The Prostate on Sexual Function and Ejaculation
NCT07566689COMPLETEDNA
110 participants
INTERVENTIONAL
Banī Suwayf, Egypt
Started: Apr 3, 2024
Rezum FIM Optimization Study
NCT02940392COMPLETEDNA
15 participants
INTERVENTIONAL
La Romana, Dominican Republic
Started: Mar 19, 2012
Comparative Study Between Rezum and Tamsulosin
NCT07169773COMPLETEDNA
94 participants
INTERVENTIONAL
Cairo, Egypt
Started: May 1, 2022
Safety and Efficacy Study for the Treatment of BPH (Enlarged Prostate)
NCT01912339COMPLETEDNA
197 participants
INTERVENTIONAL
Tucson, United States +14 more
Started: Jul 1, 2013