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Aripiprazole
Treatment for Bipolar Disorder
Typical Dosage: 10-30mg daily
Effectiveness
85%
Safety Score
50%
Clinical Trials
81
Participants
20K
Comparative Safety Scale(Higher is safer)
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50
DangerousModerateSafe
Treatment Details
Dosage Range
10-30mg daily
Time to Effect
1-2 weeks
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
9(Treat 9 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
12(Treat 12 patients to see 1 additional serious adverse event)
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$800
Monitoring:$900
Side Effect Mgmt:$200
Total Annual:$1,900
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$55,000/QALY
QALYs Gained
0.6
Outcome-Based Costs
Cost per Responder
$3,166.7
Cost per Remission
$5,428.6
Comparison vs Quetiapine
Cost Difference
$-100/year
Less expensive
QALY Difference
+0.05 QALYs
Better outcomes
Dominance
No dominance
Aripiprazole Outcomes
for Bipolar Disorder
Efficacy Outcomes
Overall Effectiveness
+85%
Response Rate
+60%
Remission Rate
+35%
Common Side Effects
Akathisia
+20%
Nausea
+12%
Insomnia
+12%
Weight gain
+10%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
18 completed trials for Aripiprazole in Bipolar Disorder
Metabolic Effects of Switching to Aripiprazole in Patients With Bipolar Disorders
NCT00845988COMPLETEDPHASE4
28 participants
INTERVENTIONAL
Seongnam-si, South Korea
Started: Dec 1, 2008
Aripiprazole in Late Life Bipolar Disorder
NCT00194038COMPLETEDPHASE4
20 participants
INTERVENTIONAL
Started: Apr 1, 2004
Aripiprazole in Children and Adolescents With Bipolar I Disorder
NCT00110461COMPLETEDPHASE3
296 participants
INTERVENTIONAL
Scottsdale, United States +52 more
Started: Mar 1, 2005
Drug-drug Interaction Study of Aripiprazole and Lamotrigine in Patients With Bipolar Type I Disorder
NCT00321516COMPLETEDPHASE1
20 participants
INTERVENTIONAL
Philadelphia, United States +3 more
Started: Jul 1, 2006
Study of Aripiprazole (Abilify) Versus Placebo in Children With Subsyndromal Bipolar Disorder
NCT00194012COMPLETEDPHASE3
62 participants
INTERVENTIONAL
Cleveland, United States
Started: Aug 1, 2004
A Trial of Multiple-doses of Aripiprazole in Adults With Schizophrenia or Bipolar 1 Disorder
NCT04030143COMPLETEDPHASE1, PHASE2
266 participants
INTERVENTIONAL
Little Rock, United States +18 more
Started: Aug 1, 2019
12- Week Open Label Treatment of Refractory Bipolar Depression
NCT00223496COMPLETEDPHASE4
32 participants
INTERVENTIONAL
San Antonio, United States
Started: Sep 1, 2004
Study of Aripiprazole in Patients With Bipolar I Disorder
NCT00257972COMPLETEDPHASE3
400 participants
INTERVENTIONAL
Little Rock, United States +89 more
Started: Oct 1, 2004
Aripiprazole in the Treatment of Bipolar Depression
NCT00226317COMPLETEDNA
20 participants
INTERVENTIONAL
Cambridge, United States
Started: Apr 1, 2004
An Open-Label Trial of Aripiprazole in Children and Adolescents With Bipolar Disorder
NCT00221416COMPLETEDPHASE3
30 participants
INTERVENTIONAL
Started: Jun 1, 2005
Study of Aripiprazole (Abilify) in Children With Symptoms of Mania
NCT00194077COMPLETEDPHASE3
60 participants
INTERVENTIONAL
Cleveland, United States
Started: Aug 1, 2004
Aripiprazole in Patients With Acute Mania
NCT00095511COMPLETEDPHASE3
615 participants
INTERVENTIONAL
Tuscaloosa, United States +37 more
Started: Jun 1, 2004
Study of Aripiprazole in Patients With a History of Bipolar Disorder
NCT00036348COMPLETEDPHASE3
INTERVENTIONAL
Birmingham, United States +18 more
Started: Mar 1, 2000
Study of Aripiprazole in the Treatment of Patients With Acute Symptoms in Bipolar Disorder
NCT00036101COMPLETEDPHASE3
INTERVENTIONAL
Tuscaloosa, United States +26 more
Started: Feb 1, 2002
Abilify in Bipolar Disorder for 24 Weeks Treatment Effectiveness
NCT00545675COMPLETEDPHASE4
146 participants
INTERVENTIONAL
Seoul, South Korea
Started: Dec 1, 2007
Efficacy and Safety of Aripiprazole in Patients With Schizophrenia or Bipolar Disorder
NCT00216723COMPLETED
3K participants
OBSERVATIONAL
Seoul, South Korea +1 more
Started: Apr 1, 2004
Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression Episode
NCT00080314COMPLETEDPHASE3
400 participants
INTERVENTIONAL
Tuscaloosa, United States +27 more
Started: Jan 1, 2004
Aripiprazole for the Treatment of Mania in Children and Adolescents With Bipolar Disorder
NCT00181779COMPLETEDPHASE4
20 participants
INTERVENTIONAL
Cambridge, United States
Started: Feb 1, 2003
Showing 20 of 82 total trials