Booting Earth Optimization System
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Disulfiram
Treatment for Cocaine use disorders
Typical Dosage: 125-500mg daily
Effectiveness
55%
Safety Score
55%
Clinical Trials
40
Participants
3K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
125-500mg daily
Time to Effect
1-2 weeks
Treatment Duration
6-12 months
Evidence Quality
MODERATENumber Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
100(Treat 100 patients to see 1 additional serious adverse event)
Confidence Score
65%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$800
Monitoring:$800
Side Effect Mgmt:$100
Total Annual:$1,700
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$100,000/QALY
QALYs Gained
0.15
Outcome-Based Costs
Cost per Responder
$3,778
Cost per Remission
$6,800
Disulfiram Outcomes
for Cocaine use disorders
Efficacy Outcomes
Overall Effectiveness
+55%
Response Rate
+45%
Remission Rate
+25%
Common Side Effects
Headache
+15%
Fatigue/drowsiness
+10%
Metallic or garlic taste
+10%
Hepatotoxicity (elevated liver enzymes)
+3%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov