Booting Earth Optimization System
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Condition
Clinical trials and treatment information for Colon and rectum cancer
Ranked by evidence volume first. Medicine has spent centuries ranking things by vibes. This is an improvement.
Comparative Safety Scale(Higher is safer)
Time to Effect
1-3 months
Duration
Until progression or up to 2 years
Response Rate
50%
Remission Rate
10%
Number Needed to Treat (NNT)
3
Common Side Effects:
Annual Cost of Care
Drug Cost
$150,000
Monitoring
$10,000
Side Effects
$8,000
Total Annual
$168,000
Cost-Effectiveness
MODERATEQALYs Gained
1.5
ICER
$112,000/QALY
Cost per Remission
$1,680,000
Cost per Responder
$336,000
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
6-9 weeks
Duration
6 months (adjuvant) or until progression (metastatic)
Response Rate
45%
Remission Rate
5%
Number Needed to Treat (NNT)
7
Common Side Effects:
Annual Cost of Care
Drug Cost
$20,000
Monitoring
$15,000
Side Effects
$10,000
Total Annual
$45,000
Cost-Effectiveness
GOODQALYs Gained
1.2
ICER
$60,000/QALY
Cost per Remission
$900,000
Cost per Responder
$100,000
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
6-9 weeks
Duration
Until progression
Response Rate
40%
Remission Rate
5%
Common Side Effects:
Annual Cost of Care
Drug Cost
$15,000
Monitoring
$15,000
Side Effects
$10,000
Total Annual
$40,000
Cost-Effectiveness
GOODQALYs Gained
0.8
ICER
$80,000/QALY
Cost per Remission
$800,000
Cost per Responder
$100,000
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
1-3 months
Duration
Until progression
Response Rate
60%
Remission Rate
5%
Number Needed to Treat (NNT)
8
Common Side Effects:
Annual Cost of Care
Drug Cost
$110,000
Monitoring
$17,000
Side Effects
$15,000
Total Annual
$142,000
Cost-Effectiveness
POORQALYs Gained
0.2
ICER
$180,000/QALY
Cost per Remission
$2,840,000
Cost per Responder
$236,667
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
1-3 months
Duration
Until progression
Response Rate
60%
Remission Rate
5%
Number Needed to Treat (NNT)
8
Common Side Effects:
Annual Cost of Care
Drug Cost
$95,000
Monitoring
$17,000
Side Effects
$15,000
Total Annual
$127,000
Cost-Effectiveness
MODERATEQALYs Gained
0.2
ICER
$115,000/QALY
Cost per Remission
$2,540,000
Cost per Responder
$211,667
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
6-9 weeks
Duration
6 months (adjuvant) or until progression (metastatic)
Response Rate
30%
Remission Rate
3%
Number Needed to Treat (NNT)
9
Common Side Effects:
Annual Cost of Care
Drug Cost
$18,000
Monitoring
$10,000
Side Effects
$5,000
Total Annual
$33,000
Cost-Effectiveness
EXCELLENTQALYs Gained
1
ICER
$30,000/QALY
Cost per Remission
$1,100,000
Cost per Responder
$110,000
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
2-4 months
Duration
Until progression or unacceptable toxicity
Response Rate
5%
Remission Rate
1%
Number Needed to Treat (NNT)
9
Common Side Effects:
Annual Cost of Care
Drug Cost
$180,000
Monitoring
$8,000
Side Effects
$7,000
Total Annual
$195,000
Cost-Effectiveness
POORQALYs Gained
0.15
ICER
$400,000/QALY
Cost per Remission
$19,500,000
Cost per Responder
$3,900,000
Clinical Trial Phases: