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Hirschsprung's Disease Pull-through Procedure
Treatment for Digestive congenital anomalies
Effectiveness
90%
Safety Score
48%
Clinical Trials
7
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
48
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate surgical relief of obstruction, functional improvement over 3-6 months
Treatment Duration
Acute (surgical), 1-2 weeks hospitalization, long-term follow-up (years)
Evidence Quality
MODERATEConfidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$500
Monitoring:$80,000
Side Effect Mgmt:$10,000
Total Annual:$90,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
68
Outcome-Based Costs
Cost per Responder
$100,556
Cost per Remission
$106,471
Hirschsprung's Disease Pull-through Procedure Outcomes
for Digestive congenital anomalies
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+90%
Remission Rate
+85%
Common Side Effects
Hirschsprung-associated enterocolitis (HAEC)
+20%
Anastomotic stricture
+10%
Fecal incontinence/soiling
+20%
Constipation
+15%
Anastomotic leak
+3%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
2 active trials recruiting for Hirschsprung's Disease Pull-through Procedure in Digestive congenital anomalies
Long-term Qualitative and Quantitative Outcomes of Children With Hirschsprung's Disease and Anorectal Malformations
NCT05450991RECRUITING
1.2K participants
OBSERVATIONAL
Liverpool, United Kingdom
Started: Jan 25, 2022
Robot/Laparoscopic-Assisted Transanal Transection Duhamel Versus Modified Soave Pull-Through for TCA
NCT07343622NOT YET RECRUITINGNA
50 participants
INTERVENTIONAL
Zunyi, China
Started: Jan 30, 2026
Completed Clinical Trials
3 completed trials for Hirschsprung's Disease Pull-through Procedure in Digestive congenital anomalies
Minimally Invasive Surgical Intervention for Hirschsprung's Disease in Pediatric Patients
NCT06874686COMPLETED
1.05K participants
OBSERVATIONAL
Hanoi, Vietnam
Started: Jan 1, 2017
Minimally Invasive Surgical Intervention for Hirschsprung Disease
NCT06880666COMPLETEDNA
23 participants
INTERVENTIONAL
Hanoi, Vietnam
Started: Jan 1, 2020
Laparoscopic-Assisted Transanal Pull-Through for Hirschsprung Disease in Pediatric:Short and Intermediate Outcomes of Two Different Techniques
NCT07186647COMPLETEDPHASE4
40 participants
INTERVENTIONAL
Cairo, Egypt
Started: Sep 1, 2020