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Posterior Sagittal Anorectoplasty (PSARP) for Imperforate Anus
Treatment for Digestive congenital anomalies
Effectiveness
88%
Safety Score
48%
Clinical Trials
1
Participants
8K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
48
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate anatomical correction, functional bowel control develops over 1-3 years
Treatment Duration
Acute (staged surgical), 1-2 weeks hospitalization, long-term follow-up and bowel management (years)
Evidence Quality
MODERATEConfidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$500
Monitoring:$70,000
Side Effect Mgmt:$10,000
Total Annual:$80,500
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
65
Outcome-Based Costs
Cost per Responder
$89,444
Cost per Remission
$100,625
Posterior Sagittal Anorectoplasty (PSARP) for Imperforate Anus Outcomes
for Digestive congenital anomalies
Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+90%
Remission Rate
+80%
Common Side Effects
Fecal incontinence/soiling
+35%
Constipation
+45%
Anal stricture
+15%
Wound infection
+7%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
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Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
1 completed trial for Posterior Sagittal Anorectoplasty (PSARP) for Imperforate Anus in Digestive congenital anomalies
Rectovestibular Fistula Which Surgical Approaches?
NCT04970160COMPLETED
84 participants
OBSERVATIONAL
Started: Jan 1, 2016