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Cognitive Behavioral Therapy (CBT)
Treatment for Fibromyalgia
Typical Dosage: 1-hour sessions, 8-12 weeks
Effectiveness
72%
Safety Score
95%
Clinical Trials
55
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
95
DangerousModerateSafe
Treatment Details
Dosage Range
1-hour sessions, 8-12 weeks
Time to Effect
8-12 weeks
Treatment Duration
8-12 weekly sessions, then maintenance
Evidence Quality
HIGHNumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
9(Treat 9 patients to see 1 additional serious adverse event)
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$1,500
Side Effect Mgmt:$50
Total Annual:$1,550
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$15,000/QALY
QALYs Gained
0.09
Outcome-Based Costs
Cost per Responder
$2,818.18
Cost per Remission
$51,666.67
Cognitive Behavioral Therapy (CBT) Outcomes
for Fibromyalgia
Efficacy Outcomes
Overall Effectiveness
+72%
Response Rate
+55%
Remission Rate
+3%
Common Side Effects
Initial emotional discomfort
+20%
Time commitment
+15%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
3 active trials recruiting for Cognitive Behavioral Therapy (CBT) in Fibromyalgia
Objective Measurement of Pain Regulation in Individuals Who Have Received Internet-delivered Exposure-based Cognitive Behavior Therapy
NCT07054333RECRUITINGNA
50 participants
INTERVENTIONAL
Stockholm, Sweden +1 more
Started: Jul 8, 2025
Self-regulation of Real-time fMRI Brain Activity in Chronic Pain
NCT07023523RECRUITINGNA
36 participants
INTERVENTIONAL
Boston, United States
Started: Oct 31, 2025
The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia
NCT07465991RECRUITINGNA
142 participants
INTERVENTIONAL
Oxford, United Kingdom +1 more
Started: Jan 1, 2026
Completed Clinical Trials
16 completed trials for Cognitive Behavioral Therapy (CBT) in Fibromyalgia
Exposure-based Cognitive Behavior Therapy vs Traditional Cognitive Behavior Therapy for Fibromyalgia
NCT05058911COMPLETEDNA
274 participants
INTERVENTIONAL
Solna, Sweden +1 more
Started: Sep 22, 2021
Sleep and Pain Interventions in Fibromyalgia
NCT02001077COMPLETEDNA
113 participants
INTERVENTIONAL
Gainesville, United States
Started: Feb 1, 2009
Drug and Talk Therapy for Fibromyalgia
NCT01038323COMPLETEDPHASE4
58 participants
INTERVENTIONAL
Indianapolis, United States
Started: Dec 1, 2009
Adding Neuromodulation Technique to Cognitive Behavior Therapy on Fibromyalgia in Postmenopausal Women
NCT07533487COMPLETEDNA
60 participants
INTERVENTIONAL
Cairo, Egypt
Started: Sep 1, 2022
Pilot Study of Internet-based Cognitive Behavior Therapy for Fibromyalgia
NCT01468961COMPLETEDNA
41 participants
INTERVENTIONAL
Stockholm, Sweden
Started: Nov 1, 2011
CBT Plus SMC Compared to SMC for Persistent Physical Symptoms in Secondary Care (PRINCE)
NCT02426788COMPLETEDNA
324 participants
INTERVENTIONAL
London, United Kingdom +6 more
Started: Jul 1, 2015
Web-based CBT for Insomnia Patients With Fibromyalgia
NCT03922867COMPLETEDNA
18 participants
INTERVENTIONAL
Rochester, United States
Started: Dec 3, 2019
A Pilot Study on the Use of Nociceptive Flexion Reflex for Fibromyalgia
NCT00965601COMPLETEDPHASE4
30 participants
INTERVENTIONAL
Indianapolis, United States
Started: Jul 1, 2008
The Maintaining Musculoskeletal Health Study
NCT02668003COMPLETEDNA
1K participants
INTERVENTIONAL
Aberdeen, United Kingdom +2 more
Started: May 1, 2016
Neuroimaging Effects of Cognitive Behavioral Therapy in Fibromyalgia
NCT01345344COMPLETEDNA
148 participants
INTERVENTIONAL
Charlestown, United States +1 more
Started: Dec 1, 2014
Cognitive Behavioral Therapy Trial in Fibromyalgia
NCT01004458COMPLETEDNA
48 participants
INTERVENTIONAL
Uppsala, Sweden
Started: Jan 1, 2001
Psychological Treatment of Depression in Women With Fibromyalgia
NCT02711020COMPLETEDNA
110 participants
INTERVENTIONAL
Barcelona, Spain +3 more
Started: Mar 1, 2016
Effectiveness of CPI With and Without Cognitive BT on Pain QOL in Fibromyalgia Patient
NCT07154498COMPLETEDNA
66 participants
INTERVENTIONAL
Burewala, Pakistan
Started: Aug 1, 2024
Meditation Awareness Training for the Treatment of Fibromyalgia Syndrome
NCT02800720COMPLETEDNA
148 participants
INTERVENTIONAL
Started: Nov 1, 2012
Sleep and Pain Interventions in Women With Fibromyalgia
NCT03744156COMPLETEDNA
131 participants
INTERVENTIONAL
Columbia, United States
Started: Feb 7, 2019
Promoting Health in People With Fibromyalgia
NCT00167271COMPLETEDNA
72 participants
INTERVENTIONAL
Pittsburgh, United States
Started: Oct 1, 2002
Showing 20 of 59 total trials