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Pregabalin
Treatment for Fibromyalgia
Typical Dosage: 150-450mg daily
Effectiveness
65%
Safety Score
58%
Clinical Trials
57
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
58
DangerousModerateSafe
Treatment Details
Dosage Range
150-450mg daily
Time to Effect
1-2 weeks
Treatment Duration
Long-term
Evidence Quality
HIGHNumber Needed to Treat (NNT)
9(Treat 9 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
8(Treat 8 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$720
Monitoring:$500
Side Effect Mgmt:$150
Total Annual:$1,370
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$60,000/QALY
QALYs Gained
0.04
Outcome-Based Costs
Cost per Responder
$3,425
Cost per Remission
$27,400
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
2 active trials recruiting for Pregabalin in Fibromyalgia
The Efficacy and Safety of Pregabalin Combined With Dexmedetomidine in Patients With Fibromyalgia
NCT07230197RECRUITINGNA
400 participants
INTERVENTIONAL
Beijing, China
Started: Sep 30, 2025
Efficacy and Safety of Pregabalin/Tizanidine vs. Pregabalin in Patients With Fibromyalgia
NCT07382921NOT YET RECRUITINGNA
164 participants
INTERVENTIONAL
Beijing, China
Started: Jan 30, 2026
Completed Clinical Trials
17 completed trials for Pregabalin in Fibromyalgia
A Study of the Efficacy and Safety of Pregabalin for the Treatment of Fibromyalgia
NCT00645398COMPLETEDPHASE3
751 participants
INTERVENTIONAL
Birmingham, United States +101 more
Started: Sep 1, 2004
Fixed Versus Flexible Dosing of Pregabalin in Patients With Fibromyalgia
NCT01226667COMPLETEDPHASE4
174 participants
INTERVENTIONAL
Beverly Hills, United States +4 more
Started: Jul 1, 2010
Randomized, Double-Blind, Placebo-Controlled Trial Of Pregabalin In Patients With Fibromyalgia.
NCT00333866COMPLETEDPHASE3
747 participants
INTERVENTIONAL
Warrawong, Australia +73 more
Started: Jul 1, 2006
A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin In Patients With Fibromyalgia
NCT00830128COMPLETEDPHASE3
106 participants
INTERVENTIONAL
Yotukaidou, Japan +18 more
Started: Jul 1, 2009
Pregabalin In Adolescent Patients With Fibromyalgia
NCT01020526COMPLETEDPHASE4
63 participants
INTERVENTIONAL
Los Angeles, United States +25 more
Started: Sep 1, 2010
Brain Response to Single Dose of Pregabalin in Fibromyalgia
NCT02639533COMPLETEDPHASE2, PHASE3
27 participants
INTERVENTIONAL
Started: Dec 1, 2014
A Phase 3b Multicenter Study of Pregabalin in Fibromyalgia Subjects Who Have Comorbid Depression
NCT01432236COMPLETEDPHASE3
197 participants
INTERVENTIONAL
Tucson, United States +36 more
Started: Oct 1, 2011
A Study For Pregabalin In Patients With Fibromyalgia
NCT01387607COMPLETEDPHASE3
343 participants
INTERVENTIONAL
Bengbu, China +21 more
Started: Feb 6, 2012
A Safety Study Of Pregabalin In Fibromyalgia
NCT00282997COMPLETEDPHASE3
500 participants
INTERVENTIONAL
Little Rock, United States +71 more
Started: Feb 1, 2006
An Open-Label Trial of Pregabalin in Patients With Fibromyalgia
NCT00151528COMPLETEDPHASE3
428 participants
INTERVENTIONAL
Birmingham, United States +92 more
Started: Jan 1, 2005
This Study is An Open-Label Trial Of Pregabalin In Patients With Fibromyalgia
NCT00346034COMPLETEDPHASE3
357 participants
INTERVENTIONAL
Kelowna, Canada +50 more
Started: Dec 1, 2006
Adolescent Fibromyalgia Study
NCT01020474COMPLETEDPHASE4
107 participants
INTERVENTIONAL
Los Angeles, United States +35 more
Started: May 1, 2010
Study Of A Controlled Release Formulation Of Pregabalin In Fibromyalgia Patients
NCT01271933COMPLETEDPHASE3
441 participants
INTERVENTIONAL
Orange, United States +51 more
Started: Mar 1, 2011
An fMRI Study Of Brain Response In Patients With Fibromyalgia
NCT00760474COMPLETEDPHASE1
27 participants
INTERVENTIONAL
Ann Arbor, United States +1 more
Started: Jan 1, 2009
Trazodone and Its Augmentation With Pregabalin in the Treatment of Fibromyalgia
NCT00791739COMPLETEDPHASE4
66 participants
INTERVENTIONAL
Granada, Spain
Started: Apr 1, 2008
Randomized, Double-Blind, Placebo-Controlled Study Of Pregabalin In Patients With Fibromyalgia
NCT00830167COMPLETEDPHASE3
498 participants
INTERVENTIONAL
Nagoya, Japan +34 more
Started: Mar 1, 2009
Pregabalin Treatment for Trigger Points
NCT04600037COMPLETEDNA
40 participants
INTERVENTIONAL
Istanbul, Turkey (Türkiye)
Started: Apr 26, 2014
Showing 20 of 62 total trials