Booting Earth Optimization System
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Thank you for your patience. Your civilization is very important to us.
Condition
Clinical trials and treatment information for HIV/AIDS - Multidrug-resistant Tuberculosis without extensive drug resistance
Ranked by evidence volume first. Medicine has spent centuries ranking things by vibes. This is an improvement.
Comparative Safety Scale(Higher is safer)
Time to Effect
1-2 months for significant clinical improvement
Duration
6 months
Response Rate
90%
Remission Rate
90%
Number Needed to Treat (NNT)
2.5
Number Needed to Harm (NNH)
7
Common Side Effects:
Annual Cost of Care
Drug Cost
$40,000
Monitoring
$3,500
Side Effects
$3,000
Total Annual
$46,500
Cost-Effectiveness
EXCELLENTQALYs Gained
12
ICER
$45,000/QALY
Cost per Remission
$51,667
Cost per Responder
$51,667
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
2-3 months for significant clinical improvement
Duration
Bedaquiline component 6-9 months, total regimen 9-18 months
Response Rate
80%
Remission Rate
80%
Number Needed to Treat (NNT)
7
Number Needed to Harm (NNH)
25
Common Side Effects:
Annual Cost of Care
Drug Cost
$45,000
Monitoring
$4,000
Side Effects
$3,000
Total Annual
$52,000
Cost-Effectiveness
GOODQALYs Gained
10
ICER
$50,000/QALY
Cost per Remission
$65,000
Cost per Responder
$65,000
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
2-3 months for significant clinical improvement
Duration
Delamanid component 6-9 months, total regimen 9-18 months
Response Rate
75%
Remission Rate
75%
Number Needed to Treat (NNT)
8
Number Needed to Harm (NNH)
25
Common Side Effects:
Annual Cost of Care
Drug Cost
$40,000
Monitoring
$4,000
Side Effects
$2,500
Total Annual
$46,500
Cost-Effectiveness
GOODQALYs Gained
9
ICER
$60,000/QALY
Cost per Remission
$62,000
Cost per Responder
$62,000
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
1-2 months for significant clinical improvement
Duration
Linezolid component 6-12 months, total regimen 9-18 months
Response Rate
75%
Remission Rate
75%
Number Needed to Treat (NNT)
7
Number Needed to Harm (NNH)
5
Common Side Effects:
Annual Cost of Care
Drug Cost
$15,000
Monitoring
$6,000
Side Effects
$5,000
Total Annual
$26,000
Cost-Effectiveness
GOODQALYs Gained
8
ICER
$70,000/QALY
Cost per Remission
$34,667
Cost per Responder
$34,667
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
2-4 months for clinical improvement
Duration
Clofazimine component 6-12 months, total regimen 9-18 months
Response Rate
70%
Remission Rate
70%
Number Needed to Treat (NNT)
12
Number Needed to Harm (NNH)
15
Common Side Effects:
Annual Cost of Care
Drug Cost
$12,000
Monitoring
$2,000
Side Effects
$1,000
Total Annual
$15,000
Cost-Effectiveness
EXCELLENTQALYs Gained
7
ICER
$30,000/QALY
Cost per Remission
$21,429
Cost per Responder
$21,429
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
2-4 months for clinical improvement
Duration
Ethambutol component 6-12 months, total regimen 9-18 months
Response Rate
65%
Remission Rate
65%
Number Needed to Harm (NNH)
30
Common Side Effects:
Annual Cost of Care
Drug Cost
$11,000
Monitoring
$1,000
Side Effects
$500
Total Annual
$12,500
Cost-Effectiveness
EXCELLENTQALYs Gained
6
ICER
$15,000/QALY
Cost per Remission
$19,231
Cost per Responder
$19,231
Clinical Trial Phases: