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Lisinopril
Treatment for Hypertension
Typical Dosage: 10-40mg daily
Effectiveness
88%
Safety Score
70%
Clinical Trials
80
Participants
500K
Comparative Safety Scale(Higher is safer)
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Meth💀
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Antibiotics💉
Tylenol💊
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Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
10-40mg daily
Time to Effect
1-2 weeks
Treatment Duration
lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
35(Treat 35 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
10(Treat 10 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$20
Monitoring:$150
Side Effect Mgmt:$50
Total Annual:$220
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$7,000/QALY
QALYs Gained
0.5
Outcome-Based Costs
Cost per Responder
$367
Comparison vs No treatment
Cost Difference
$-220/year
Less expensive
QALY Difference
+0.50 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Lisinopril Outcomes
for Hypertension
Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+60%
Common Side Effects
Cough
+15%
Dizziness/Orthostatic Hypotension
+5%
Hyperkalemia
+3%
Angioedema
+0.1%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
15 completed trials for Lisinopril in Hypertension
Safety Study of Lisinopril in Children and Adolescents With a Kidney Transplant
NCT01491919COMPLETEDPHASE1
26 participants
INTERVENTIONAL
Birmingham, United States +6 more
Started: Jun 1, 2012
Personalised Dose Optimisation of Zestril Supported by the Digital Blood Pressure Diary in a Primary Care Environment in England: Pragmatic Observational Pilot Study for Remote Hypertension Treatment
NCT06372470COMPLETED
20 participants
OBSERVATIONAL
Norwich, United Kingdom
Started: Apr 15, 2024
Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood Pressure
NCT00624065COMPLETEDPHASE3
348 participants
INTERVENTIONAL
Mobile, United States +75 more
Started: Mar 1, 2008
The COREG And Lisinopril Combination Therapy In Hypertensive Subjects (COSMOS) Trial
NCT00347360COMPLETEDPHASE3
654 participants
INTERVENTIONAL
Anniston, United States +150 more
Started: Jul 1, 2006
The Vascular Effects of Carvedilol Controlled Release (CR) in Abdominally Obese Hypertensive Patients
NCT00459056COMPLETEDPHASE3
25 participants
INTERVENTIONAL
Saint Paul, United States
Started: Apr 1, 2007
Comparison Of Morning And Evening Dosing Of Valsartan And Lisinopril In Patients With Diabetes
NCT00241124COMPLETEDPHASE4
1.1K participants
INTERVENTIONAL
Investigative Centers, Germany
Started: Apr 1, 2004
VALERIA: Valsartan in Combination With Lisinopril in Hypertensive Patients With Microalbuminuria
NCT00171067COMPLETEDPHASE3
134 participants
INTERVENTIONAL
Investigative Centers, Germany +1 more
Started: Jul 1, 2004
Dose Titration of Lisinopril in Children Aged 1 to 18 Years With Primary or Secondary Hypertension
NCT02184858COMPLETEDPHASE4
13 participants
INTERVENTIONAL
Ghent, Belgium
Started: Jun 25, 2014
Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and Lisinopril
NCT01258764COMPLETEDNA
2 participants
INTERVENTIONAL
La Jolla, United States
Started: Nov 1, 2010
A Study Investigating the Bioequivalence of the Fixed Dose Combination of COREG CR to COREG CR and ZESTRIL.
NCT00552708COMPLETEDPHASE1
55 participants
INTERVENTIONAL
Tacoma, United States
Started: Sep 1, 2007
CAndesartan vs LIsinopril Effects on the BRain
NCT01984164COMPLETEDPHASE2
176 participants
INTERVENTIONAL
Atlanta, United States
Started: Aug 20, 2014
Non-invasive Haemodynamic Assessment in Hypertension
NCT01996085COMPLETEDNA
144 participants
INTERVENTIONAL
Warsaw, Poland
Started: Jan 1, 2013
Series of N-of-1 Crossover Trials of Antihypertensive Therapy in Adolescents With Essential Hypertension
NCT02412761COMPLETEDNA
42 participants
INTERVENTIONAL
Houston, United States
Started: Jun 1, 2013
Comparison of Optimal Hypertension Regimens
NCT02847338COMPLETEDPHASE4
940 participants
INTERVENTIONAL
Cambridge, United Kingdom +13 more
Started: Nov 1, 2016
Evaluation of Periop Biochemical Stress Factors in Craniotomy Neurosurgical Procedure With Respect to Preop Hypertension
NCT02441842COMPLETEDPHASE4
85 participants
INTERVENTIONAL
Started: Mar 1, 2006
Showing 20 of 80 total trials