Booting Earth Optimization System
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Pentosan Polysulfate Sodium
Treatment for Interstitial Cystitis
Typical Dosage: 100mg three times daily
Effectiveness
55%
Safety Score
58%
Clinical Trials
3
Participants
5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
58
DangerousModerateSafe
Treatment Details
Dosage Range
100mg three times daily
Time to Effect
3-6 months
Treatment Duration
Lifetime
Evidence Quality
MODERATENumber Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Confidence Score
65%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$54,000
Monitoring:$1,150
Side Effect Mgmt:$200
Total Annual:$55,350
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$112,654/QALY
QALYs Gained
0.3
Outcome-Based Costs
Cost per Responder
$158,142.86
Cost per Remission
$1,107,000
Comparison vs Amitriptyline
Cost Difference
+$54,550/year
More expensive
QALY Difference
-0.20 QALYs
Worse outcomes
Dominance
No dominance
Pentosan Polysulfate Sodium Outcomes
for Interstitial Cystitis
Efficacy Outcomes
Overall Effectiveness
+55%
Response Rate
+35%
Remission Rate
+5%
Common Side Effects
Nausea
+8%
Diarrhea
+7%
Alopecia
+4%
Headache
+4%
Maculopathy
+1%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
2 completed trials for Pentosan Polysulfate Sodium in Interstitial Cystitis
A Study of Pentosan Polysulfate Sodium and the Development of Pigmentary Maculopathy and Pigmentary Retinopathy
NCT05179460COMPLETED
2 participants
OBSERVATIONAL
Titusville, United States
Started: Oct 26, 2021
Efficacy Study of Pentosan Polysulfate Sodium,Hydrodistension and Combination Therapy for Bladder Pain Syndrome
NCT01895153COMPLETED
91 participants
OBSERVATIONAL
Seoul, South Korea
Started: Apr 1, 2012