Booting Earth Optimization System
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Rapid Reversal of Anticoagulation
Treatment for Intracerebral hemorrhage
Typical Dosage: PCC (25-50 IU/kg), Vitamin K (5-10 mg IV), Idarucizumab (5g IV), Andexanet Alfa (bolus + infusion)
Effectiveness
90%
Safety Score
60%
Clinical Trials
3
Participants
8K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
PCC (25-50 IU/kg), Vitamin K (5-10 mg IV), Idarucizumab (5g IV), Andexanet Alfa (bolus + infusion)
Time to Effect
Immediate (minutes to hours)
Treatment Duration
Single dose or short course
Evidence Quality
HIGHNumber Needed to Treat (NNT)
15(Treat 15 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
25(Treat 25 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$8,000
Monitoring:$200
Side Effect Mgmt:$500
Total Annual:$8,700
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$60,000/QALY
QALYs Gained
1
Outcome-Based Costs
Cost per Responder
$34,800
Rapid Reversal of Anticoagulation Outcomes
for Intracerebral hemorrhage
Efficacy Outcomes
Overall Effectiveness
+90%
Response Rate
+90%
Common Side Effects
Thrombotic events (DVT, PE, MI, stroke)
+8%
Allergic reactions
+1%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
2 active trials recruiting for Rapid Reversal of Anticoagulation in Intracerebral hemorrhage
International Care Bundle Evaluation in Cerebral Hemorrhage Research
NCT06429332RECRUITINGPHASE4
3.5K participants
INTERVENTIONAL
Oklahoma City, United States +51 more
Started: Jan 7, 2025
Maximal Medical Treatment of Intracerebral Haemorrhage Pilot Trial - MAX-ICH Pilot Trial
NCT06648369NOT YET RECRUITINGNA
50 participants
INTERVENTIONAL
Bern, Switzerland
Started: Dec 1, 2024
Completed Clinical Trials
1 completed trial for Rapid Reversal of Anticoagulation in Intracerebral hemorrhage
The Third, Intensive Care Bundle With Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial
NCT03209258COMPLETEDNA
7.07K participants
INTERVENTIONAL
Chengdu, China
Started: Dec 12, 2017