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Intravenous Ferumoxytol
Treatment for Iron Deficiency Anemia
Typical Dosage: Total 1020 mg in 2 infusions
Effectiveness
89%
Safety Score
68%
Clinical Trials
11
Participants
7.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
68
DangerousModerateSafe
Treatment Details
Dosage Range
Total 1020 mg in 2 infusions
Time to Effect
2-4 weeks
Treatment Duration
1 week initially, then as needed
Evidence Quality
HIGHNumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
150(Treat 150 patients to see 1 additional serious adverse event)
Confidence Score
88%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$2,000
Monitoring:$2,100
Side Effect Mgmt:$100
Total Annual:$4,200
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$65,000/QALY
QALYs Gained
0.3
Outcome-Based Costs
Cost per Responder
$4,941
Cost per Remission
$5,419
Comparison vs Oral Ferrous Sulfate
Cost Difference
+$3,730/year
More expensive
QALY Difference
+0.10 QALYs
Better outcomes
Dominance
No dominance
Prescription Access Economics
Risk Assessment
Requires Monitoring
YesNeeds lab work/checkups
Intravenous Ferumoxytol Outcomes
for Iron Deficiency Anemia
Efficacy Outcomes
Overall Effectiveness
+89%
Response Rate
+85%
Remission Rate
+77.5%
Common Side Effects
Diarrhea
+4%
Nausea
+3%
Dizziness
+2%
Hypotension (transient)
+1%
Headache
+1%
Injection site reactions
+1%
Hypersensitivity/Anaphylaxis
+0.1%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
4 active trials recruiting for Intravenous Ferumoxytol in Iron Deficiency Anemia
Early Antenatal Support for Iron Deficiency Anemia
NCT04278651RECRUITINGPHASE4
80 participants
INTERVENTIONAL
Philadelphia, United States
Started: Sep 29, 2021
Sucrosomial Vs Intravenous Iron for Preoperative Anemia
NCT07287371NOT YET RECRUITINGPHASE4
75 participants
INTERVENTIONAL
Rochester, United States
Started: Dec 31, 2025
Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient
NCT04268849RECRUITINGPHASE3
104 participants
INTERVENTIONAL
Baltimore, United States
Started: Feb 27, 2020
Darbe Plus IV Iron to Decrease Transfusions While Maintaining Iron Sufficiency in Preterm Infants
NCT05340465RECRUITINGPHASE2
120 participants
INTERVENTIONAL
Seattle, United States
Started: Nov 27, 2022
Completed Clinical Trials
7 completed trials for Intravenous Ferumoxytol in Iron Deficiency Anemia
Total Dose Infusion of Ferumoxytol(1020mg) in 15 Minutes for Iron Deficiency Anemia
NCT01374919COMPLETEDNA
60 participants
INTERVENTIONAL
Baltimore, United States
Started: Jun 1, 2011
Iron Indices and Intravenous Ferumoxytol: Time to Steady State
NCT01148745COMPLETEDPHASE4
15 participants
INTERVENTIONAL
North Brunswick, United States
Started: Mar 1, 2010
Comparison of Oral Ferrous Sulfate to Intravenous Ferumoxytol in Antepartum Iron Deficiency Anemia
NCT04253626COMPLETEDPHASE3
83 participants
INTERVENTIONAL
Stanford, United States
Started: Jan 21, 2021
Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IVOR-IDA)
NCT02499354COMPLETEDPHASE2
100 participants
INTERVENTIONAL
Baltimore, United States
Started: Aug 1, 2014
Intravenous Infusions of Ferumoxytol Compared to Oral Ferrous Sulfate for the Treatment of Anemia in Pregnancy
NCT03657433COMPLETEDPHASE3
124 participants
INTERVENTIONAL
Tucson, United States
Started: Dec 17, 2018
Compare Efficacy/Safety of Repeat Doses of Ferumoxytol With Iron Sucrose in CKD Subjects With IDA and on Hemodialysis
NCT01227616COMPLETEDPHASE4
296 participants
INTERVENTIONAL
Pine Bluff, United States +42 more
Started: Aug 1, 2013
Observational Study on the Use of IV (Intravenous) Iron Therapy Among Subjects With Iron Deficiency Anemia
NCT01984554COMPLETED
551 participants
OBSERVATIONAL
Norristown, United States
Started: Sep 1, 2013