Booting Earth Optimization System
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Hydrochlorothiazide (HCTZ)
Treatment for Kidney Stones
Typical Dosage: 12.5-50mg daily
Effectiveness
75%
Safety Score
65%
Clinical Trials
7
Participants
7K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
12.5-50mg daily
Time to Effect
Weeks to months
Treatment Duration
Long-term/Lifetime
Evidence Quality
HIGHNumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
20(Treat 20 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$200
Side Effect Mgmt:$100
Total Annual:$350
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$25,000/QALY
QALYs Gained
0.9
Outcome-Based Costs
Cost per Responder
$467
Cost per Remission
$583
Hydrochlorothiazide (HCTZ) Outcomes
for Kidney Stones
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+75%
Remission Rate
+60%
Common Side Effects
Hypokalemia (low potassium)
+15%
Hypotension/Dizziness
+7%
Hyperglycemia, Hyperuricemia
+7%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
1 active trial recruiting for Hydrochlorothiazide (HCTZ) in Kidney Stones
Indapamide and Chlorthalidone to Reduce Urine Supersaturation for Kidney Stone Prevention
NCT06111885RECRUITINGPHASE2
99 participants
INTERVENTIONAL
Bern, Switzerland
Started: Oct 1, 2024
Completed Clinical Trials
3 completed trials for Hydrochlorothiazide (HCTZ) in Kidney Stones
Use of Nanotechnology Structured Water for the Prevention of Recurrent Stone Formation
NCT06681116COMPLETEDNA
325 participants
INTERVENTIONAL
Sulaymaniyah, Iraq
Started: Feb 16, 2015
Hydrochlorothiazide for Kidney Stone Recurrence Prevention
NCT03057431COMPLETEDPHASE3
416 participants
INTERVENTIONAL
Aarau, Switzerland +11 more
Started: Mar 9, 2017
Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine Calcium
NCT02711670COMPLETEDNA
10 participants
INTERVENTIONAL
New York, United States
Started: Feb 1, 2014