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Percutaneous Nephrolithotomy (PCNL)
Treatment for Kidney Stones
Effectiveness
95%
Safety Score
45%
Clinical Trials
79
Participants
45K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
45
DangerousModerateSafe
Treatment Details
Time to Effect
Immediate stone removal
Treatment Duration
Single procedure (hospitalization 2-4 days)
Evidence Quality
HIGHConfidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$2,000
Side Effect Mgmt:$1,500
Total Annual:$15,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
GOODICER
$85,000/QALY
QALYs Gained
0.9
Outcome-Based Costs
Cost per Responder
$15,789
Cost per Remission
$16,667
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
7 active trials recruiting for Percutaneous Nephrolithotomy (PCNL) in Kidney Stones
Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones
NCT06922006ACTIVE NOT RECRUITING
67 participants
OBSERVATIONAL
San Diego, United States
Started: Mar 26, 2024
Safety and Effectiveness of Antegrade Flexible Ureteroscopy-Assisted Percutaneous Nephrolithotomy for Staghorn Calculi
NCT07172373NOT YET RECRUITINGNA
420 participants
INTERVENTIONAL
Started: Oct 1, 2025
VISOR Versus PCNL for Treatment of 2-4cm Renal Stones
NCT07159503ENROLLING BY INVITATIONNA
170 participants
INTERVENTIONAL
Hangzhou, China
Started: Apr 20, 2025
FANS-Assisted Mini-PCNL for Complex Renal Stones
NCT07332286ACTIVE NOT RECRUITINGNA
30 participants
INTERVENTIONAL
Guangzhou, China
Started: Dec 19, 2025
Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy
NCT07393711NOT YET RECRUITINGNA
95 participants
INTERVENTIONAL
Aqtöbe, Kazakhstan
Started: Mar 1, 2026
Flexible Ureteroscopy With a Flexible and Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for 1-2 cm Lower Pole Kidney Stones
NCT07159035ACTIVE NOT RECRUITINGNA
640 participants
INTERVENTIONAL
Guangzhou, China
Started: Aug 28, 2025
Three Dimensional Virtual Reconstruction (3D) in Percutaneous Nephrolithotomy
NCT06797466RECRUITINGNA
100 participants
INTERVENTIONAL
Adıyaman, Turkey (Türkiye)
Started: Jan 21, 2025
Completed Clinical Trials
9 completed trials for Percutaneous Nephrolithotomy (PCNL) in Kidney Stones
Comparison of Tubeless Versus Standard Percutaneous Nephrolithotomy (PCNL) for Renal Stones
NCT07522619COMPLETEDNA
60 participants
INTERVENTIONAL
Karachi, Pakistan
Started: Nov 24, 2021
Tubeless vs Tube PCNL in Pediatric Nephrolithiasis: A Randomized Controlled Trial.
NCT07183930COMPLETEDNA
640 participants
INTERVENTIONAL
Peshawar, Pakistan
Started: Oct 1, 2024
Standard vs Mini-PCNL for the Treatment of Stone Disease
NCT04069013COMPLETEDNA
18 participants
INTERVENTIONAL
Cleveland, United States
Started: May 1, 2022
Comparison of Trifecta Analysis of Standard Versus Mini Percutaneous Nephrolithotomy in the Management of Urolithiasis
NCT06836700COMPLETEDNA
180 participants
INTERVENTIONAL
Peshawar, Pakistan
Started: Jan 10, 2022
Preoperative Prophylactic Fosfomycin Trometamol Versus 5-day Levofloxacin in Prevention of Postpercutaneous Nephrolithotomy Infectious Complications and Sepsis.
NCT07355907COMPLETEDNA
210 participants
INTERVENTIONAL
Tanta, Egypt
Started: Jan 1, 2023
Stone Access and Removal (STAR) Study
NCT06330701COMPLETEDNA
15 participants
INTERVENTIONAL
Indianapolis, United States +1 more
Started: Jan 18, 2024
The Success of Pediatric Percutaneous Nephrolithotomy
NCT04299204COMPLETEDNA
553 participants
INTERVENTIONAL
Started: Jan 15, 1998
Flexible Ureteroscopy With Tip-bendable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for Treatment of 2-3cm Renal Stones
NCT06526390COMPLETEDNA
720 participants
INTERVENTIONAL
Guangzhou, China
Started: Aug 21, 2024
Initial Clinical Experience With the MONARCH Platform, Urology for the Treatment of Kidney Stones
NCT05835323COMPLETEDNA
15 participants
INTERVENTIONAL
Orange, United States
Started: Jan 11, 2023
Showing 20 of 95 total trials