Booting Earth Optimization System
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Condition
Clinical trials and treatment information for Liver cancer due to hepatitis C
Ranked by evidence volume first. Medicine has spent centuries ranking things by vibes. This is an improvement.
Comparative Safety Scale(Higher is safer)
Time to Effect
Months to years for sustained benefit
Duration
Lifetime (immunosuppression)
Response Rate
%
Remission Rate
75%
Number Needed to Treat (NNT)
1
Common Side Effects:
Annual Cost of Care
Drug Cost
$15,000
Monitoring
$10,000
Side Effects
$7,500
Total Annual
$32,500
Cost-Effectiveness
GOODQALYs Gained
8
ICER
$150,000/QALY
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
Immediate (tumor removal), long-term survival benefit
Duration
One-time surgery, followed by surveillance
Response Rate
%
Remission Rate
60%
Number Needed to Treat (NNT)
2
Common Side Effects:
Annual Cost of Care
Drug Cost
$0
Monitoring
$3,500
Side Effects
$2,000
Total Annual
$5,500
Cost-Effectiveness
GOODQALYs Gained
5
ICER
$100,000/QALY
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
Immediate (tumor destruction)
Duration
One-time procedure, may require repeat, followed by surveillance
Response Rate
%
Remission Rate
70%
Common Side Effects:
Annual Cost of Care
Drug Cost
$0
Monitoring
$3,000
Side Effects
$750
Total Annual
$3,750
Cost-Effectiveness
EXCELLENTQALYs Gained
4
ICER
$60,000/QALY
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
1-2 months
Duration
Until disease progression or unacceptable toxicity
Response Rate
27.3%
Remission Rate
%
Number Needed to Treat (NNT)
4
Common Side Effects:
Annual Cost of Care
Drug Cost
$215,000
Monitoring
$15,000
Side Effects
$10,000
Total Annual
$240,000
Cost-Effectiveness
MODERATEQALYs Gained
1.2
ICER
$190,000/QALY
Cost per Responder
$879,121
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
1-2 months
Duration
Until disease progression or unacceptable toxicity
Response Rate
24.1%
Remission Rate
%
Common Side Effects:
Annual Cost of Care
Drug Cost
$175,000
Monitoring
$7,500
Side Effects
$5,000
Total Annual
$187,500
Cost-Effectiveness
GOODQALYs Gained
0.6
ICER
$120,000/QALY
Cost per Responder
$778,008
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
1-2 months
Duration
Multiple sessions (1-3+ per year), ongoing surveillance
Response Rate
60%
Remission Rate
%
Number Needed to Treat (NNT)
4
Common Side Effects:
Annual Cost of Care
Drug Cost
$0
Monitoring
$7,500
Side Effects
$2,000
Total Annual
$9,500
Cost-Effectiveness
GOODQALYs Gained
1
ICER
$80,000/QALY
Cost per Responder
$15,833
Clinical Trial Phases: