Booting Earth Optimization System
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Condition
Clinical trials and treatment information for Malignant neoplasm of bone and articular cartilage
Ranked by evidence volume first. Medicine has spent centuries ranking things by vibes. This is an improvement.
Comparative Safety Scale(Higher is safer)
Time to Effect
Immediate (tumor removal), 3-12 months for recovery/rehabilitation
Duration
Single procedure, followed by rehabilitation for months to years
Response Rate
95%
Remission Rate
90%
Common Side Effects:
Annual Cost of Care
Drug Cost
$500
Monitoring
$15,000
Side Effects
$20,000
Total Annual
$35,500
Cost-Effectiveness
EXCELLENTQALYs Gained
4.5
Cost per Remission
$39,444
Cost per Responder
$37,368
Comparative Safety Scale(Higher is safer)
Time to Effect
Weeks to months (during treatment cycles)
Duration
6-12 months typically
Response Rate
70%
Remission Rate
50%
Common Side Effects:
Annual Cost of Care
Drug Cost
$100,000
Monitoring
$20,000
Side Effects
$60,000
Total Annual
$180,000
Cost-Effectiveness
GOODQALYs Gained
3.5
Cost per Remission
$360,000
Cost per Responder
$257,143
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
Weeks to months (during and after treatment course)
Duration
4-8 weeks (daily fractions)
Response Rate
70%
Remission Rate
60%
Common Side Effects:
Annual Cost of Care
Drug Cost
$200
Monitoring
$15,000
Side Effects
$10,000
Total Annual
$25,200
Cost-Effectiveness
GOODQALYs Gained
3
Cost per Remission
$42,000
Cost per Responder
$36,000
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
Weeks (engraftment and initial recovery), months for full recovery
Duration
1-3 months inpatient, prolonged outpatient recovery
Response Rate
40%
Remission Rate
30%
Common Side Effects:
Annual Cost of Care
Drug Cost
$75,000
Monitoring
$75,000
Side Effects
$50,000
Total Annual
$200,000
Cost-Effectiveness
POORQALYs Gained
2
ICER
$250,000/QALY
Cost per Remission
$666,667
Cost per Responder
$500,000
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
Months (during treatment course)
Duration
48 weeks (twice weekly for 24 weeks, then weekly for 24 weeks)
Response Rate
%
Remission Rate
%
Common Side Effects:
Annual Cost of Care
Drug Cost
$120,000
Monitoring
$1,000
Side Effects
$2,000
Total Annual
$123,000
Cost-Effectiveness
POORQALYs Gained
0.2
ICER
$250,000/QALY
Clinical Trial Phases:
Comparative Safety Scale(Higher is safer)
Time to Effect
1-3 months
Duration
Until progression or unacceptable toxicity (months to years)
Response Rate
15%
Remission Rate
3%
Common Side Effects:
Annual Cost of Care
Drug Cost
$180,000
Monitoring
$10,000
Side Effects
$5,000
Total Annual
$195,000
Cost-Effectiveness
POORQALYs Gained
0.3
ICER
$250,000/QALY
Cost per Remission
$6,500,000
Cost per Responder
$1,300,000
Clinical Trial Phases: