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Postnatal Myelomeningocele Repair
Treatment for Neural tube defects
Typical Dosage: N/A (surgical procedure)
Effectiveness
75%
Safety Score
55%
Clinical Trials
4
Participants
50K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
55
DangerousModerateSafe
Treatment Details
Dosage Range
N/A (surgical procedure)
Time to Effect
Immediate surgical correction, long-term care
Treatment Duration
Single surgical intervention (typically within 72 hours of birth)
Evidence Quality
HIGHNumber Needed to Harm (NNH)
10(Treat 10 patients to see 1 additional serious adverse event)
Confidence Score
95%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$5,000
Side Effect Mgmt:$20,000
Total Annual:$90,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
12
Outcome-Based Costs
Cost per Responder
$90,000
Postnatal Myelomeningocele Repair Outcomes
for Neural tube defects
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+100%
Common Side Effects
Surgical site infection
+7%
Hydrocephalus requiring ventriculoperitoneal shunt
+80%
CSF leak
+10%
Meningitis
+3%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
3 active trials recruiting for Postnatal Myelomeningocele Repair in Neural tube defects
Sleep-disordered Breathing in Infants With Myelomeningocele
NCT04251806ACTIVE NOT RECRUITING
173 participants
OBSERVATIONAL
Birmingham, United States +8 more
Started: Jul 21, 2020
Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial
NCT04652908RECRUITINGPHASE1, PHASE2
55 participants
INTERVENTIONAL
Sacramento, United States
Started: Jun 21, 2021
The Role of CSF in Chiari II Brain Malformation
NCT06560788NOT YET RECRUITING
18 participants
OBSERVATIONAL
Started: Sep 1, 2024
Completed Clinical Trials
1 completed trial for Postnatal Myelomeningocele Repair in Neural tube defects
Management of Myelomeningocele Study (MOMS)
NCT00060606COMPLETEDNA
183 participants
INTERVENTIONAL
San Francisco, United States +2 more
Started: Feb 1, 2003