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Gabapentin
Treatment for Peripheral Neuropathy
Typical Dosage: 900-3600 mg daily in 3 divided doses
Effectiveness
75%
Safety Score
62%
Clinical Trials
72
Participants
30K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
62
DangerousModerateSafe
Treatment Details
Dosage Range
900-3600 mg daily in 3 divided doses
Time to Effect
1-2 weeks
Treatment Duration
lifetime
Evidence Quality
MODERATENumber Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
8(Treat 8 patients to see 1 additional serious adverse event)
Confidence Score
83%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$180
Monitoring:$250
Side Effect Mgmt:$100
Total Annual:$530
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$15,000/QALY
QALYs Gained
0.06
Outcome-Based Costs
Cost per Responder
$1,104.17
Cost per Remission
$7,571.43
Comparison vs Pregabalin
Cost Difference
$-220/year
Less expensive
QALY Difference
-0.01 QALYs
Worse outcomes
Dominance
No dominance
Gabapentin Outcomes
for Peripheral Neuropathy
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+48%
Remission Rate
+7%
Common Side Effects
Dizziness
+20%
Somnolence
+20%
Peripheral edema
+7%
Fatigue
+5%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
15 completed trials for Gabapentin in Peripheral Neuropathy
A Study on the Efficacy and Safety of Gabapentin in the Treatment of Patients With Painful Diabetic Neuropathy
NCT00644748COMPLETEDPHASE4
95 participants
INTERVENTIONAL
Fortaleza, Brazil +9 more
Started: May 1, 2003
A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN)
NCT00643760COMPLETEDPHASE2
421 participants
INTERVENTIONAL
Alabaster, United States +89 more
Started: Mar 1, 2008
Botulinum Toxin Type A in Diabetic Peripheral Neuropathy
NCT05296759COMPLETEDPHASE4
30 participants
INTERVENTIONAL
Alexandria, Egypt
Started: Feb 1, 2021
Safety and Efficacy of Gabapentin in Diabetic Peripheral Neuropathy
NCT00712439COMPLETEDPHASE2
147 participants
INTERVENTIONAL
Started: Apr 1, 2006
Neuropathic Pain Management
NCT01263132COMPLETEDPHASE3
104 participants
INTERVENTIONAL
Pachuca, Mexico
Started: Feb 1, 2008
Trazodone/Gabapentin Fixed Dose Combination Products in Painful Diabetic Neuropathy
NCT03749642COMPLETEDPHASE2
240 participants
INTERVENTIONAL
Litomyšl, 570 01, Czechia +29 more
Started: Nov 22, 2018
A Study to Compare Safety and Efficacy of Tramadol Hydrochloride/Acetaminophen With Gabapentin in Participants With Diabetic Neuropathy
NCT00634543COMPLETEDPHASE4
162 participants
INTERVENTIONAL
Started: Dec 1, 2006
An Open-Label Comparison of Duloxetine to Other Alternatives for the Management of Diabetic Peripheral Neuropathic Pain
NCT00385671COMPLETEDPHASE4
407 participants
INTERVENTIONAL
Torrance, United States +8 more
Started: Sep 1, 2006
Therapeutic Interventions For Pain Induced By Vincristine Treatment For Childhood Acute Lymphoblastic Leukemia (ALL)
NCT01506453COMPLETEDPHASE2
51 participants
INTERVENTIONAL
Memphis, United States
Started: Jan 24, 2012
Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy
NCT00027963COMPLETEDPHASE3
100 participants
INTERVENTIONAL
Scottsdale, United States +22 more
Started: Feb 1, 2002
Efficacy and Safety of Gabapentin/B-complex Versus Pregabalin in Diabetic Peripheral Neuropathy Pain Management
NCT01364298COMPLETEDPHASE4
353 participants
INTERVENTIONAL
Mexico City, Mexico
Started: Apr 1, 2011
A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions
NCT00904202COMPLETEDPHASE4
62 participants
INTERVENTIONAL
Birmingham, United States +6 more
Started: Jan 1, 2003
Comparative Clinical Study Evaluating the Possible Efficacy of Duloxetine, Gabapentin and Lacosamide on Oxaliplatin-Induced Peripheral Neuropathy in Cancer Patients
NCT05510856COMPLETEDPHASE4
93 participants
INTERVENTIONAL
Tanta, Egypt
Started: Sep 1, 2022
Preoperative Gabapentine for Carpal Tunnel
NCT01632215COMPLETEDPHASE3
40 participants
INTERVENTIONAL
Started: Mar 1, 2010
A Controlled Clinical Trial Assessing the Efficacy of Vitamin B Prophylaxis in Attenuating Paclitaxel-induced Neuropathy and the Imperative Use of Gabapentin in Diabetic Ovarian Cancer Patients and the Potential Effect on Disease Response.
NCT07191587COMPLETEDNA
146 participants
INTERVENTIONAL
Cairo, Egypt
Started: Dec 1, 2024
Showing 20 of 76 total trials