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Tranexamic Acid (TXA)
Treatment for Subarachnoid hemorrhage
Typical Dosage: Loading dose 1g IV, then 1g every 6-8 hours IV
Effectiveness
68%
Safety Score
65%
Clinical Trials
1
Participants
3K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
65
DangerousModerateSafe
Treatment Details
Dosage Range
Loading dose 1g IV, then 1g every 6-8 hours IV
Time to Effect
Immediate
Treatment Duration
24-72 hours (acute)
Evidence Quality
MODERATENumber Needed to Treat (NNT)
8(Treat 8 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
75(Treat 75 patients to see 1 additional serious adverse event)
Confidence Score
70%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$100
Monitoring:$50
Side Effect Mgmt:$100
Total Annual:$250
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$70,000/QALY
QALYs Gained
0.1
Outcome-Based Costs
Cost per Responder
$1,250
Tranexamic Acid (TXA) Outcomes
for Subarachnoid hemorrhage
Efficacy Outcomes
Overall Effectiveness
+68%
Response Rate
+20%
Common Side Effects
Nausea/vomiting
+12%
Diarrhea
+7%
Thrombotic events (DVT/PE)
+3%
Seizures
+0.5%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
1 completed trial for Tranexamic Acid (TXA) in Subarachnoid hemorrhage
Ultra-early Tranexamic Acid After Subarachnoid Hemorrhage.
NCT02684812COMPLETEDPHASE2, PHASE3
955 participants
INTERVENTIONAL
Amsterdam, Netherlands
Started: Jul 16, 2012