Booting Earth Optimization System
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Metronidazole
Treatment for Tetanus
Typical Dosage: 500mg IV every 6-8 hours or 500mg orally twice daily
Effectiveness
88%
Safety Score
70%
Clinical Trials
1
Participants
10K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
500mg IV every 6-8 hours or 500mg orally twice daily
Time to Effect
1-2 days (to inhibit bacterial growth)
Treatment Duration
7-14 days
Evidence Quality
HIGHNumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
50(Treat 50 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$50
Monitoring:$10
Side Effect Mgmt:$5
Total Annual:$65
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
12
Outcome-Based Costs
Cost per Responder
$68
Cost per Remission
$81
Comparison vs Penicillin G
Cost Difference
$-10/year
Less expensive
QALY Difference
+0.50 QALYs
Better outcomes
Dominance
DOMINATESBetter + cheaper
Metronidazole Outcomes
for Tetanus
Efficacy Outcomes
Overall Effectiveness
+88%
Response Rate
+95%
Remission Rate
+80%
Common Side Effects
Nausea
+10%
Diarrhea
+8%
Metallic taste
+5%
Headache
+3%
Sources:
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
1 completed trial for Metronidazole in Tetanus
The Role of the Intestinal Microbiome in Enteric and Systemic Vaccine Immune Responses
NCT02538211COMPLETEDNA
63 participants
INTERVENTIONAL
Amsterdam, Netherlands
Started: Sep 1, 2015