Booting Earth Optimization System
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Pseudoephedrine
Treatment for Upper respiratory infections
Typical Dosage: 30-60mg every 4-6 hours (max 240mg/day)
Effectiveness
75%
Safety Score
70%
Clinical Trials
24
Participants
25K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
70
DangerousModerateSafe
Treatment Details
Dosage Range
30-60mg every 4-6 hours (max 240mg/day)
Time to Effect
30-60 minutes
Treatment Duration
As needed, 3-7 days for URI symptoms
Evidence Quality
HIGHNumber Needed to Treat (NNT)
5(Treat 5 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
1200(Treat 1200 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$15
Monitoring:$600
Side Effect Mgmt:$0
Total Annual:$615
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.005
Outcome-Based Costs
Cost per Responder
$18.75
Pseudoephedrine Outcomes
for Upper respiratory infections
Efficacy Outcomes
Overall Effectiveness
+75%
Response Rate
+80%
Common Side Effects
Insomnia
+15%
Nervousness/restlessness
+10%
Headache
+5%
WARNING: LIMITED TRIALS AVAILABLE
You can search for trials, but you probably can't join any because the 1% Treaty hasn't passed yet. Most trials are severely limited by lack of funding and bureaucratic barriers. Help change this!
Active Clinical Trials
1 active trial recruiting for Pseudoephedrine in Upper respiratory infections
Nasal Decongestant to Reduce Perioperative Adverse Events in Children With Upper Respiratory Track Infections Having Anesthesia.
NCT07000877RECRUITINGPHASE4
200 participants
INTERVENTIONAL
Perth, Australia
Started: Jun 25, 2025
Completed Clinical Trials
16 completed trials for Pseudoephedrine in Upper respiratory infections
Warming Sensation Intensity and Acceptability of the Flavour, Local Tolerability of Paracetamol 500 mg + Pseudoephedrine 30 mg Syrup in Patients Suffering a URTI
NCT01586962COMPLETEDPHASE3
56 participants
INTERVENTIONAL
Montreal, Canada
Started: May 1, 2012
Safety and Efficacy Study of Guaifenesin and Pseudoephedrine for Symptomatic Therapy to Treat Acute RTI
NCT01202279COMPLETEDPHASE4
1.18K participants
INTERVENTIONAL
Mesa, United States +23 more
Started: Oct 1, 2009
Acetylsalicylic Acid Combined With Pseudoephedrine in Common Cold
NCT00963443COMPLETEDPHASE3
833 participants
INTERVENTIONAL
Cardiff, United Kingdom
Started: Sep 1, 2009
Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold
NCT00378144COMPLETEDPHASE4
469 participants
INTERVENTIONAL
Wilrijk, Belgium
Started: Jan 1, 2007
LiveSpo Navax® Supports the Treatment of Acute Rhinosinusitis and Otitis Media
NCT05804123COMPLETEDNA
175 participants
INTERVENTIONAL
Thái Bình, Vietnam
Started: Oct 28, 2021
Placebo and Active Controlled Study to Assess Efficacy and Tolerability of Aspirin Plus Pseudoephedrine
NCT01062360COMPLETEDPHASE3
1.02K participants
INTERVENTIONAL
New York, United States +58 more
Started: Dec 23, 2005
The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza.
NCT02246166COMPLETEDPHASE4
53 participants
INTERVENTIONAL
Shanghai, China +1 more
Started: Jan 1, 2015
A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold
NCT01744106COMPLETEDPHASE3
565 participants
INTERVENTIONAL
Anaheim, United States +10 more
Started: Nov 1, 2012
CHAO Tos: Codeina, HederA Helix, LevOdropropizina Para la TOS
NCT06907355COMPLETEDPHASE4
196 participants
INTERVENTIONAL
Santiago, Chile
Started: May 13, 2025
A Study of Nasal Glucagon in Participants With a Common Cold
NCT02778100COMPLETEDPHASE1
36 participants
INTERVENTIONAL
Mount Royal, Canada
Started: Mar 1, 2013
Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects With a Common Cold
NCT00452270COMPLETEDPHASE3
60 participants
INTERVENTIONAL
Cardiff, United Kingdom
Started: Mar 1, 2007
Bioequivalence Study of Ibuprofen 200 mg + Pseudoephedrine HCL 30 mg Tablets Under Fed Conditions
NCT01132222COMPLETEDPHASE1
34 participants
INTERVENTIONAL
Bangalore, India
Started: Sep 1, 2004
Bioequivalency Study of Ibuprofen 200 mg and Pseudoephedrine HCL 30 mg Tablets of Dr. Reddy's Under Fasting Conditions
NCT01131780COMPLETEDPHASE1
32 participants
INTERVENTIONAL
Bangalore, India
Started: Oct 1, 2004
Bioequivalence Study of Naproxen Sodium 220 mg & Pseudoephedrine HCl 120 mg ER Tablets of Dr. Reddy's Under Fed Conditions
NCT01131767COMPLETEDPHASE1
26 participants
INTERVENTIONAL
Bangalore, India
Started: Jul 1, 2004
Bioequivalence Study of Naproxen Sodium 220 mg & Pseudoephedrine HCl 120 mg ER Tablets of Dr. Reddy's Under Fasting Conditions
NCT01131728COMPLETEDPHASE1
26 participants
INTERVENTIONAL
Bangalore, India
Started: Jul 1, 2004
Efficacy and Safety of Combination of Brompheniramine and Phenylephrine for the Symptoms Relief of Rhinitis
NCT01393548COMPLETEDPHASE3
879 participants
INTERVENTIONAL
Guarulhos, Brazil
Started: Aug 1, 2014
Showing 20 of 24 total trials